“Finding the trial for the patient, rather than the patient for the trial”
The Precision-Panc Master Protocol is a “portal” protocol for patients with known or suspected pancreatic cancer to be accrued through multiple centres in the UK, with the option of being subsequently enrolled into PRIMUS (Pancreatic canceR Individualised Multi-arm Umbrella Study) examining different treatment regimens and/or biomarker development.
Eligible patients will undergo tumour biopsy and blood collection for molecular profiling at a central laboratory and the results may be used to inform enrolment to PRIMUS studies.
The overall aim of this research study is to improve the outcomes of patients with pancreatic cancer. It is designed to achieve this by studying of the make up of the cancer, in order to find out what the most effective treatment for each individual patient might be. It also aims to learn more about when, how and why people develop pancreatic cancer. We also hope to be able to predict which people are at risk of developing pancreatic cancer.
The Precision Panc platform is open to recruitment at:
- Aberdeen Royal Infirmary
- Addenbrookes Hospital, Cambridge
- Bristol Haematology and Oncology Centre
- The Christie, Manchester
- Glasgow Royal Infirmary
- Imperial College Healthcare Trust
- Manchester Royal Infirmary
- Nottingham University Hospital
- Royal Free London
- Royal Marsden Hospital
- University College London Hospital
- Weston Park Hospital, Sheffield